A Review of Molecular Characterization of Classical Swine Fever Virus (CSFV)

作者：Zhang H^*; Cao H W; Wu Z J; Cui Y D

来源：Israel Journal of Veterinary Medicine, 2011, 66(3): 89-95.

• classical swine fever
• CSFV
• genome structure
• protein function

Classical swine fever (CSF), a listed disease of the Office International des Epizooties (OIE), is an important, highly contagious and often fatal pig disease with widespread economic implications. The classical swine fever virus (CSFV) is the causative agent of this disease. The virus is an enveloped, non-segmented, positive-strand RNA virus that belongs to the Pestivirus genus within the Flaviviridae family. The CSFV genome contains a single large open reading frame (ORF), a 5'-nontranslated region (5'-NTR) and a 3'-nontranslated region (3'-NTR). During the past decade, much progress on the CSFV molecular characterization have been achieved and more than thirty CSFV genomes being sequenced and annotated. However, the genome structure and its protein functions remain to be further elucidated. We present here an overview of CSFV molecular characterization and potential future directions for research.

• 出版日期2011-9
• 单位黑龙江八一农垦大学