Nonenzymatic Electrochemical Detection of Glucose Based on Palladium-Single-Walled Carbon Nanotube Hybrid Nanostructures

作者：Meng Ling; Jin Juan; Yang Gaixiu; Lu Tianhong; Zhang Hui^*; Cai Chenxin

来源：Analytical Chemistry, 2009, 81(17): 7271-7280.

DOI：10.1021/ac901005p

A new electrocatalyst, palladium nanoparticle-single-walled carbon nanotube (Pd-SWNTs) hybrid nanostructure, for the nonenzymatic oxidation of glucose was developed and characterized by X-ray diffraction (XRD) and the transmission electron microscope (TEM). The hybrid nanostructures were prepared by depositing Palladium nanoparticles with average diameters of 4-5 nm on the surface of single-walled carbon nanotubes (SWNTs) via chemical reduction of the precursor (Pd(2 )). Me electrocatalyst showed good electrocatalytic activity toward the oxidation of glucose in the neutral phosphate buffer solution (PBS, pH 7.4) even in the presence of a high concentration of chloride ions. A nonenzymatic amperometric glucose sensor was developed with the use of the Pd-SWNT nanostructure as an electrocatalyst. The sensor had good electrocatalytic activity toward oxidation of glucose and exhibited a rapid response (ca.3 s), a low detection limit (0.2 /- 0.05 mu M), a wide and useful linear range (0.5-17 mM), and high sensitivity (similar to 160 mu A mM(-1) cm(-2)) as well as good stability and repeatability. In addition, the common interfering species, such as ascorbic acid, uric acid, 4-acetamidophenol, 3,4-dihydroxyphenylacetic acid, and so forth did not cause any interference due to the use of a low detection potential (-0.35 V vs SCE). The sensor can also be used for quantification of the concentration of glucose in real clinical samples. Therefore, this work has demonstrated a simple and effective sensing platform for nonenzymatic detection of glucose.

• 出版日期2009-9-1
• 单位南京师范大学