A Novel Amine Receptor Based on the Binol Scaffold Functions as a Highly Effective Chiral Shift Reagent for Carboxylic Acids

作者:Ma Qingzhu; Ma Minshan; Tian Hongying; Ye Xiaoxia; Xiao Hongping; Chen Lian hui*; Lei Xinxiang
来源:Organic Letters, 2012, 14(23): 5813-5815.
DOI:10.1021/ol3027686

摘要

A "smart" receptor has been newly synthesized. NMR studies demonstrated that the receptor functions as a chiral shift reagent that is highly effective for determining the enantiomeric purity of a series of carboxylic acids, particularly those that have an a-oxygen atom.