Development of an injection molded ethylene-vinyl acetate copolymer (EVA) intravaginal insert for the delivery of progesterone to cattle

作者：Cappadoro A J^*; Luna J A

来源：Animal Reproduction Science, 2015, 158: 104-108.

DOI：10.1016/j.anireprosci.2015.05.007

• Intravaginal drug delivery
• Controlled release
• Progesterone delivery
• Ethylene-vinyl acetate
• Estrous control

The purpose of this study was to develop a new injection-molded intravaginal insert manufactured from ethylene-vinyl acetate containing progesterone for a 7-day insertion period in cattle. The manufacturing process resulted in a reduction in the residual drug compared to the silicone insert available while still maintaining biological performance.

• 出版日期2015-7