Mitral valve replacement complicated by iatrogenic left ventricular outflow obstruction and paravalvular leak: case report and review of literature

作者：Lee Justin Z^*; Tey Kai R; Mizyed Ahmad; Hennemeyer Charles T; Janardhanan Rajesh; Lotun Kapildeo

来源：BMC Cardiovascular Disorders, 2015, 15(1): 119.

DOI：10.1186/s12872-015-0108-z

• Left ventricular outflow tract obstruction
• Paravalvular leak
• Septal ablation

Background: Left ventricular outflow tract (LVOT) obstruction and paravalvular leak (PVL) are relatively uncommon, but are serious complications of prosthetic valve replacement.
Case presentation: We present a case that displays the unique therapeutic challenges of treating a patient who developed both LVOT obstruction and mitral PVL after undergoing surgical aortic and mitral valve replacement (MVR). We also describe the use of alcohol septal ablation and albumin-glutaraldehyde (BioGlue) for septal ablation to percutaneously treat the patient's LVOT obstruction, followed by use of an Amplatzer vascular plug for percutaneous closure of an antero-medial mitral PVL associated with severe regurgitation.
Conclusion: Percutaneous interventional management of these entities may be considered as an initial therapeutic option, especially in high-risk patients with significant morbidity and mortality of repeat surgical operations.

• 出版日期2015-10-9