A new tigliane-type diterpene from Euphorbia dracunculoides Lam

作者：Dai, Lin-Feng; Liang, Qian; Liu, Tie; He, Ming-Yu; Zhao, Ping; Xu, Wen-Hui^*

来源：Natural Product Research, 2016, 30(14): 1639-1645.

DOI：10.1080/14786419.2015.1129334

• Euphorbia dracunculoides
• diterpenoids
• hydroperoxy
• tigliane

One new tigliane-type diterpene, 4-deoxy-4(beta)H-8-hydroperoxyphorbol-12-benzoate-13-isobutyrate (1), together with two known diterpenoids, 3-acetyl-5,8-dibenzoyl-14 alpha-propanoyl-13,17-epoxy-7-myrsinaone diterpene with C9-C10 cyclised to form an additional lactone ring (2), Euphodendriane A (3) have been isolated from the whole plants of Euphorbia dracunculoides Lam. Their structures were elucidated by means of extensive spectroscopic analysis (NMR and HR-ESI-MS) and comparison with data reported in the literature. This is the first isolation of 8-hydroperoxy tigliane diterpene (1) from the genus of Euphorbia. All compounds were evaluated for their antifungal activities.
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• 出版日期2016
• 单位西南林业大学