Association between obesity with disease-free survival and overall survival in triple-negative breast cancer: A meta-analysis

作者：Mei Lin; He Lin^*; Song Yuhua; Lv Yang; Zhang Lijiu; Hao Fengxi; Xu Mengmeng

来源：Medicine, 2018, 97(19): e0719.

DOI：10.1097/MD.0000000000010719

• disease-free survival
• meta-analysis
• obesity
• overall survival
• triple-negative breast cancer

Objective:To investigate the relationship between obesity and disease-free survival (DFS) and overall survival (OS) of triple-negative breast cancer.Methods:Citations were searched in PubMed, Cochrane Library, and Web of Science. Random effect model meta-analysis was conducted by using Revman software version 5.0, and publication bias was evaluated by creating Egger regression with STATA software version 12.Results:Nine studies (4412 patients) were included for DFS meta-analysis, 8 studies (4392 patients) include for OS meta-analysis. There were no statistical significances between obesity with DFS (P=.60) and OS (P=.71) in triple-negative breast cancer (TNBC) patients.Conclusion:Obesity has no impact on DFS and OS in patients with TNBC.

• 出版日期2018-5
• 单位安徽医科大学; 青岛大学