Dietary total antioxidant capacity from different assays in relation to serum C-reactive protein among young Japanese women

作者：Kobayashi Satomi; Murakami Kentaro; Sasaki Satoshi^*; Uenishi Kazuhiro; Yamasaki Mitsuyo; Hayabuchi Hitomi; Goda Toshinao; Oka Jun; Baba Keiko; Ohki Kazuko; Watanabe Reiko; Sugiyamama Yoshiko

来源：Nutrition Journal, 2012, 11: 91.

DOI：10.1186/1475-2891-11-91

• Dietary total antioxidant capacity
• Serum C-reactive protein
• Diet history questionnaire
• Young Japanese women
• Epidemiology

Background: The association between dietary total antioxidant capacity (TAC) from different assays and serum C-reactive protein (CRP) has not been assessed in non-Western populations. We examined the association between dietary TAC and serum CRP concentration in young Japanese women using different four TAC assays. %26lt;br%26gt;Methods: The subjects were 443 young Japanese women aged 18-22 years. Dietary TAC was assessed with a self-administered diet history questionnaire and the TAC value of each food using the following four assays: ferric reducing ability of plasma (FRAP); oxygen radical absorbance capacity (ORAC); Trolox equivalent antioxidant capacity (TEAC); and total radical-trapping antioxidant parameter (TRAP). Serum CRP concentrations were measured by highly sensitive nephelometry. %26lt;br%26gt;Results: The major contributor to dietary TAC was green, barley, and oolong tea (FRAP: 53%, ORAC: 45%, TEAC: 36%, and TRAP: 44%). The prevalence of elevated CRP concentrations (%26gt;= 1 mg/L) was 5.6%. TAC from FRAP was inversely associated with serum CRP concentrations (adjusted odds ratio [OR] for elevated CRP concentration in high [compared with low] dietary TAC group: 0.39 [95% confidence interval (CI): 0.16-0.98]; P = 0.04). TAC from ORAC was inversely associated with CRP, although the association was not significant (OR: 0.48 [95% CI: 0.20-1.14]; P = 0.10). TAC from TEAC was inversely associated with CRP (OR: 0.32 [95% CI: 0.12-0.82]; P = 0.02), as was TAC from TRAP (OR: 0.31 [95% CI: 0.12-0.81]; P = 0.02). %26lt;br%26gt;Conclusions: Dietary TAC was inversely associated with serum CRP concentration in young Japanese women regardless of assay. Further studies are needed in other populations to confirm these results.

• 出版日期2012-10-30