科研之友
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摘要
The azlB locus of Bacillus subtilis was defined previously by a mutation conferring resistance to a leucine analog, 4-azaleucine (J. B. Ward, Jr., and S. A. Zahler, J. Bacteriol, 116:727-735, 1973), In this report, azlB is shown to be the first gene of an operon apparently involved in branched-chain amino acid transport, The product of the azlB gene is an Lrp-like protein that negatively regulates expression of the azlBCDEF operon, Resistance to 4-azaleucine in azlB mutants is due to overproduction of AzlC and AzlD, two novel hydrophobic proteins.
- 出版日期1997-9
