A second generation MRI contrast agent for imaging zinc ions in vivo

作者:De Leon Rodriguez Luis M*; Lubag Angelo J M; Lopez Jorge A; Andreu de Riquer Gabriel; Alvarado Monzon Jose C; Sherry A Dean
来源:Medchemcomm, 2012, 3(4): 480-483.
DOI:10.1039/c2md00301e

摘要

A Zn2+ specific GdDOTA derivative containing two bis-(3-pyrazolyl) units was prepared and characterized. Unlike a previously reported Zn2+ binding agent, the new agent binds to human albumin both in the presence and absence of Zn2+.

  • 出版日期2012-4