Diverse reactivity of 2-formylphenylboronic acid with secondary amines: synthesis of 3-amino-substituted benzoxaboroles

作者：Adamczyk Wozniak Agnieszka; Madura Izabela; Velders Aldrik H; Sporzynski Andrzej^*

来源：Tetrahedron Letters, 2010, 51(47): 6181-6185.

DOI：10.1016/j.tetlet.2010.09.091

• Boronic acids
• Benzoxaboroles
• Boroxins
• Secondary amines
• Crystal structure

In the reaction of 2-formylphenylboronic acid with secondary amines different products are formed depending on the structure of the amines. For aliphatic amines the reaction proceeds with the formation of 3-amino-substituted benzoxaboroles or with the formation of complexed boroxins. A crystal structure of the benzoxaborole with a thiomorpholinyl substituent was determined.

• 出版日期2010-11-24