A new pyrazoline-based probe of quenched fluorescent reversible recognition for Cu2+ and its application in cells

作者:Zhang, Ying-Peng*; Dong, Yu-Ying; Yang, Yun-Shang*; Guo, Hui-Chen; Cao, Bi-Xia; Sun, Shi-Qi
来源:Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy , 2017, 177: 147-152.
DOI:10.1016/j.saa.2017.01.042

摘要

Anew pyrazoline-based probe D was designed and synthesized, which can be used as a highly sensitive, selective and reversible recognizing fluorescent to detect Cu2+. The recognition properties of this compound was investigated by UV-vis absorption and fluorescence spectrophotometry. The results showed that the probe D forms a 1:1 complex with Cu2+ and displayed a linear fluorescence response to Cu2+ with a detection limit of 1.94 x 10(-7) M. In addition, the probe have a good biocompatibility in living cells.