An efficient synthesis of 3-indolyl-3-hydroxy oxindoles and 3,3-di(indolyl)indolin-2-ones catalyzed by sulfonated beta-CD as a supramolecular catalyst in water

作者：Tayade Yogesh A; Patil Dipak R; Wagh Yogesh B; Jangle Asha D; Dalal Dipak S^*

来源：Tetrahedron Letters, 2015, 56(5): 666-673.

DOI：10.1016/j.tetlet.2014.12.012

• Sulfonated-beta-cyclodextrin
• 3,3-Di(indolyl)indolin-2-ones
• Recyclable catalyst

Sulfonated-beta-cyclodextrin (beta-CD-SO3H) promoted efficient and fast electrophilic substitution reaction of indoles with various isatins reflux in water is reported affording various 3-indolyl-3-hydroxy oxindoles and 3,3-di(indolyl)indolin-2-ones in good to excellent yields in short reaction time.

• 出版日期2015-1-28