A novel NBD-based pH "on-off" fluorescent probe equipped with the N-phenylpiperazine group for lysosome imaging

作者:Ma, Zhao; Lin, Yuxing; Chen, Hui; Du, Lupei; Li, Minyong*
来源:RSC Advances, 2016, 6(104): 102773-102777.
DOI:10.1039/c6ra16996a

摘要

A novel PET-based fluorescent probe (LN6) targeting to lysosome was found from the synthesized NBD derivatives. This probe was equipped with the novel lysosome-targeted N-phenylpiperazine group, and could be employed to image lysosome and detect its pH change without any washing steps.