A comparative study: Diffusion weighted whole body imaging with background body signal suppression and hybrid Positron Emission Computed Tomography on detecting lesions in oncologic clinics

作者：Wang Nianfei; Zhang Mingjun; Sun Tong; Chen Huaidong; Huang Zhonglian; Yan Long; Wang Longsheng; Li Fei; Chen Zhendong^*

来源：European Journal of Radiology, 2012, 81(7): 1662-1666.

DOI：10.1016/j.ejrad.2011.03.047

• Magnetic resonance imaging
• Diffusion weighted MR imaging
• PET/CT
• Tumor

Objective: To compare diffusion weighted whole body imaging with background body signal suppression (DWIBS) with hybrid Positron Emission Computed Tomography (HPET/CT) on clinical value in oncology.
Methods: 43 patients with oncological diseases were enrolled in our hospital from October, 2008 to April, 2010. All the cases underwent DWIBS and HPET/CT within 14 days. Combined with other imagings, lesions detected by both modalities were evaluated. Lesions were confirmed by pathology, cytology or clinical diagnosis (needed no less than 6 months and three times follow-up).
Results: The overall detection rate of the DWIBS and HPET/CT were 90.3% (261/289), 86.6% (251/289), concordant ratio of the two modalities was 88.2% (255/289). There was no statistical difference between DWIBS and HPET/CT on detecting lesions (P > 0.05). HPET/CT was significantly more sensitive in detecting lesions in lung (P < 0.05), whereas DWIBS was more sensitive in identifying lesions in brain and bone (P < 0.05). With regard to finding lesions in liver and lymph node, the two procedures had no significant difference (P > 0.05).
Conclusion: DWIBS and HPET/CT have a certain degree of consistency in terms of identifying lesions. However, they have advantages and disadvantages in some organs or tissues, which should be taken into full consideration in clinical practice.

• 出版日期2012-7
• 单位安徽医科大学