Acute pancreatitis in pregnancy: an overview

作者：Papadakis Efstathios P; Sarigianni Maria; Mikhailidis Dimitri P; Mamopoulos Apostolos^*; Karagiannis Vasilios

来源：European Journal of Obstetrics & Gynecology and Reproductive Biology, 2011, 159(2): 261-266.

DOI：10.1016/j.ejogrb.2011.07.037

• Pregnancy
• Acute pancreatitis
• Gallstones
• Hypertriglyceridemia
• Laparoscopic surgery

Acute pancreatitis is rare in pregnancy but it is associated with increased incidence of maternal and fetal mortality. It should be considered in the differential diagnosis of upper quadrant abdominal pain with or without nausea and vomiting. The commonest identified causes of acute pancreatitis in pregnancy are gallstones, alcohol and hypertriglyceridemia. The main laboratory finding is increased amylase activity. Appropriate investigations include ultrasound of the right upper quadrant and measurement of serum triglycerides and ionized calcium. Management of gallstone pancreatitis is controversial, although laparoscopic cholecystectomy and endoscopic retrograde cholangiopancreatography (ERCP) are often used and may be associated with lower complication rates. In hypertriglyceridemia-induced acute pancreatitis co-3 fatty acids and even therapeutic plasma exchange can be used. We also discuss preventive measures.

• 出版日期2011-12