Aminopropylated PEG as a novel, eco-friendly and biodegradable basic catalyst for bis-Michael addition to alpha,beta-unsaturated ketones under solvent-free conditions

作者：Khan Tabassum; Siddiqui Zeba N^*

来源：Applied Organometallic Chemistry, 2014, 28(8): 620-630.

DOI：10.1002/aoc.3171

• NH2-PEG
• bis-Michael addition products
• solvent-free conditions

A solvent-free and highly efficient protocol has been developed for the synthesis of novel bis-Michael addition products (3a-o) using aminopropylated PEG-6000 (NH2-PEG) as a biodegradable and recyclable catalyst in excellent yields under solvent-free conditions. Other remarkable features of this environmentally benign protocol are shorter reaction time, tolerance of a wide range of C-H-activated acids, high yield of products, and simple experimental and work-up procedure as compared to conventional methods. The NH2-PEG catalyst is characterized by using FT-IR, powder XRD and scanning electron microscopy-energy dispersion X-ray spectrometric analyses. The catalyst can be recycled several times without significant loss of its catalytic activity.

• 出版日期2014-8