Novel opportunities for next-generation probiotics targeting metabolic syndrome

作者:Cani Patrice D*; Van Hul Matthias
来源:Current Opinion in Biotechnology, 2015, 32: 21-27.
DOI:10.1016/j.copbio.2014.10.006

摘要

Various studies have described the beneficial effects of specific bacteria on the characteristics of metabolic syndrome. Intestinal microbiota might therefore represent a modifiable trait for translational intervention to improve the metabolic profiles of obese and type 2 diabetic patients. However, identifying potential probiotic strains that can effectively colonize the gastrointestinal tract and significantly affect host metabolism has been challenging. This review aims to summarize the notable advances and contributions in the field that may prove useful for identifying next-generation probiotics that target metabolic syndrome and its related disorders.

  • 出版日期2015-4