Novel varicella-zoster virus glycoprotein E gene mutations associated with genotypes A and D

作者:Schmidt Chanasit Jonas*; Bleymehl Karoline; Schaed Susanne G; Gross Gerd; Ulrich Rainer G; Doerr Hans Wilhelm
来源:Journal of Clinical Microbiology, 2008, 46(1): 325-327.
DOI:10.1128/JCM.01735-07

摘要

Here, we describe the association of certain varicella-zoster virus (VZV) genotypes with unique glycoprotein E (gE) gene mutations. Within 45 analyzed VZV wild-type strains of genotypes A and D, five novel gE mutations were discovered. A statistically significant (P < 0.0001) association of certain gE mutations with VZV genotype D was found.