Direct Solid-Phase Optical Measurements in Flow Systems: A Review

作者：Rocha Fabio R P; Raimundo Ivo M Jr; Teixeira Leonardo S G^*

来源：Analytical Letters, 2011, 44(1-3): 528-559.

DOI：10.1080/00032719.2010.500790

• Flow analysis
• Flow-through optosensors
• Infrared spectroscopy
• Luminescence
• Reflectance
• Review
• Solid-phase spectrophotometry

Measurements based on absorption, reflectance, or luminescence of molecular species or complex ions can be carried out directly on a solid support simultaneously to the retention of the analyte. The use of this strategy in flow-based systems is advantageous in view of the reproducible handling of solutions in retention and elution steps of the analyte. This approach can be exploited to increase sensitivity, minimize reagent consumption as well as waste generation, improve selectivity or for simultaneous determination based on selective retention or differences in sorption rates of the analytes. This review focuses on the main characteristics of direct solid-phase measurements in flow systems, including the discussion of advantages and limitations and practical guidelines to the successful implementation of this approach. Selected applications in diverse fields, such as pharmaceutical, food, and environmental analysis are discussed.

• 出版日期2011