A mitochondrial drug to treat AML

作者:Pinton Paolo*
来源:Blood, 2017, 129(19): 2597-2599.
DOI:10.1182/blood-2017-03-773200

摘要

In this issue of Blood, Liyanage et al demonstrate that acute myeloid leukemia (AML) cells exhibit increased mitochondrial DNA (mtDNA) content and that the 2',3'-dideoxycytidine (ddC; an inhibitor of mtDNA biosynthesis already used in clinic) selectively kills leukemia cells.(1)

  • 出版日期2017-5-11