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摘要
As current diagnostic methods for constipation are invasive and the diagnostic effects are not ideal, this paper researches how to use the noninvasive detection equipment to obtain the gastrointestinal physiological information. The nonlinear analysis methods were taken to analyze human colon dynamics and to find out the difference between normal people and constipated patients, then to provide references for clinical diagnosis of the constipation. Colonic pressure data from 8 healthy and 10 constipated subjects were analyzed. Firstly, the breathing, coughing, electromagnetic interference noise in the colonic pressure data were filtered by thresholds and the Ensemble Empirical Mode Decomposition (EEMD). Then, the colonic contractile frequency, motility index and the average peak of peristaltic wave were extracted to characterize the colonic dynamic properties. Finally, the feature parameters between healthy and constipated subjects were compared by using the t test. Analysis shows that the number of contractions and the motility indexes of healthy subjects are different from that of the patients with constipation (p<0.05), and they have statistically significance for distinguish the healthy subjects and the patients with constipation, but the average peak of peristaltic wave does not. So it suggests that the number of contractions and motility indexes could be used in the noninvasive detection for diagnostics of the healthy subjects and patients with the constipation.
- 出版日期2015
- 单位上海交通大学
