Alum (KAl(SO4)(2)center dot 12H(2)O) Catalyzed Multicomponent Transformation: Simple, Efficient, and Green Route to Synthesis of Functionalized Spiro[chromeno[2,3-d]pyrimidine-5,3 '-indoline]-tetraones in Ionic Liquid Media

作者：Moghaddam Mirhosseini Mojtaba; Bazgir Ayoob; Mehdi Mohammad Akhondi; Ghahremanzadeh Ramin^*

来源：Chinese Journal of Chemistry, 2012, 30(3): 709-714.

DOI：10.1002/cjoc.201280014

• isatin
• spirooxindoles
• dimedone
• barbituric acid
• ionic liquids

The combination of isatin, barbituric acid, and cyclohexane-1,3-dione derivatives in the presence of alum (KAl(SO4)2 center dot 12H2O) as a catalyst for 15 min was found to be a suitable and efficient method for the synthesis of spiro[chromeno[2,3-d]pyrimidine-5,3'-indoline]-tetraones.

• 出版日期2012-3