A novel fluorogenic probe for monoamine oxidase assays

作者：Lu You You; Wang Yu Guang; Dai Bin; Dai Yi Qi; Wang Zhao; Fu Zheng Wei; Zhu Qing^*

来源：Chinese Chemical Letters, 2008, 19(8): 947-950.

DOI：10.1016/j.cclet.2008.05.032

• Monoamine oxidase
• Fluorogenic probe
• Assay

Monoamine oxidase is flavoenzymes, widely distributed in mammals. It is well recognized that MAOs serve an important role in metabolism that they have close relationship with health. Along with the discoveries between MAOs and neurotic disease, more and more studies have been jumped in. In this paper, we design a new probe for assaying the activities of MAOs. The results showed that the probe [7-(3-aminopropoxy)coumarin] is simple, effective and sensitive for MAOB.

• 出版日期2008-8
• 单位浙江工业大学