Measuring Skin Autofluorescence

作者：Stirban A^*; Heinemann L

来源：Diabetes, Stoffwechsel und Herz, 2013, 22(4): 225-236.

• autofluorescence
• advanced glycation endproducts
• prediction
• diabetes complications

Measuring HbA(1c) as a parameter mirroring the quality of glycaemic control within the previous eight to twelve weeks has markedly influenced not only diabetes therapy, but also our understanding of how diabetes complications develop. Results from the DCCT/EDIC study have strengthened the glycaemic memory concept's postulation that metabolic control over several years predicts the development of diabetic complications. While HbA(1c) might not represent the optimal parameter, other substances with longer persistence - such as those referred to as advanced glycation endproducts - are probably more effective as a substrate of metabolic memory. Recent years have seen methods develop for rapid, easy and non-invasive skin autofluorescence assessment, a parameter

• 出版日期2013-8-20