A case of vomiting in an anorexic achalasic patient

作者：Scarpellini E; Cafarotti S; Cesario A; Lococo F; Margaritora S; Gabrielli M; Tortora A; Ga**arrini A^*; Granone P

来源：European Review for Medical and Pharmacological Sciences, 2012, 16: 44-47.

• Achalasia
• Anorexia nervosa
• Wernicke syndrome
• Thiamine

Wernicke%26apos;s encephalopathy is a neurological disorder caused by thiamine (vitamin B1) deficiency characterized by vertigo, ataxia, and mental confusion. Wernicke%26apos;s encephalopathy has a causative association with alcoholism but recently there has been an increased prevalence also in other clinical conditions. In literature potentially fatal Wernicke%26apos;s encephalopathy onset in an advanced achalasia has been previously reported only once. We describe for the first time an improvement of achalasic symptoms in a young patient affected by end-stage achalasia and anorexia nervosa (coming from ineffective Heller-Dor myotomy) after vitamin B1 supplementation. This case report suggest a potential positive impact of B1 supplementation on end-stage achalasic patients and requires systematic studies to confirm this observation.

• 出版日期2012-10