科研之友
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摘要
Morphogenetic movement of cells is of significant importance in embryogenesis. It is necessary to identify the final position and configuration of the embryo's tissues and share the positional information in differentiation. The healing of tissular injuries happens in the adult organism due to the cell layers' movement, and the directed macrophages migration to the nidus of infection assists the neutralization of inflammatory processes. Owing to the good level of knowledge, the fruit fly D. melanogaster is a perfect model object for the study of morphogenetic events in embryogenesis in connection with the cells movement. The description of Drosophila embryogenesis, mechanisms of ventral furrow formation, elongation of the germ band, and its contraction accompanied by dorsal closure was given. During these processes the movement of epithelial cells and the entire epithelial strata happens. The information about the genetic regulation of morphogenetic movement of D. melanogaster taking into consideration the scale of evolutionary conservatism of the cascades of the main signal, which control these processes in vertebrates, is presented.
- 出版日期2009-10
