A Procedure for Transforming indoles into Indolequinones

作者:Eastabrook Andrew S; Wang Christy; Davison Emma K; Sperry Jonathan*
来源:Journal of Organic Chemistry, 2015, 80(2): 1006-1017.
DOI:10.1021/jo502509s

摘要

A procedure that converts a series of structurally diverse, readily available indole derivatives to their corresponding indolequinones is described. The three-step route commences with an iridium catalyzed C-H borylation to give a 7-borylindole that upon oxidationhydrolysis affords the 7-hydroxyindole. Subsequent oxidation provides the indolequinone.

  • 出版日期2015-1-16