A case of erythema multiforme drug eruption associated with erythrodermic psoriasis induced by sofosbuvir and daclatasvir

作者：Wang, Y.; Liu, P.

来源：Journal of Clinical Pharmacy and Therapeutics, 2017, 42(1): 108-110.

DOI：10.1111/jcpt.12467

• daclatasvir
• erythema multiforme drug eruption
• erythrodermic psoriasis
• side effect
• sofosbuvir

What is known and the objectiveSofosbuvir (SOF) and daclatasvir (DCV) have revolutionized the treatment of hepatitis C virus and now represent the preferred therapy for this disease. Limited data are available on the dermatological side effects resulting from co-administration of SOF and DCV.
Case descriptionWe report a case of an erythema multiforme drug eruption associated with erythrodermic psoriasis induced by SOF and DCV. After ceasing treatment, the skin condition significantly improved.
What is new and conclusionWe should pay attention to adverse skin reactions resulting from SOF and DCV, especially if the patient has a pre-existing dermatosis.

• 出版日期2017-2
• 单位中国医科大学