Atomic Force Microscopy Combined with Optical Microscopy for Cells Investigation

作者：Cascione Mariafrancesca; De Matteis Valeria; Rinaldi Rosaria; Leporatti Stefano

来源：Microscopy Research and Technique, 2017, 80(1): 109-123.

DOI：10.1002/jemt.22696

<jats:title>ABSTRACT</jats:title><jats:p>This review reports on the combined use of the atomic force microscopy (AFM) and several type of optical/fluorescence/laser scanning microscopy for investigating cells. It is shown that the hybrid systems of AFM with optical‐derived microscopies enable to study in detail cell surface properties (such as topography), their mechanical properties (e.g., Young's modulus) mechanotransduction phenomena and allow to gain insight into biological‐related pathways and mechanisms in the complex nanoworld of cells. <jats:italic>Microsc. Res. Tech. 80:109–123, 2017</jats:italic>.

• 出版日期2017-1