An Efficient Method for the Synthesis of 3-Aryl-4,7-phenanthroline Derivatives Catalyzed by Iodine

作者：Yin, Ming-Yue; Zhang, Mei-Mei; Wang, Wei; Li, Yu-Ling; Wang, Xiang-Shan^*

来源：Journal of Heterocyclic Chemistry, 2012, 49(5): 1239-1242.

DOI：10.1002/jhet.954

• HIGHLY SELECTIVE METHOD
• ANTITUMOR-ACTIVITY
• FACILE SYNTHESIS
• 1,10-PHENANTHROLINE
• COPPER(II)
• COMPLEXES

A mild and efficient method for the synthesis of 3-aryl-4,7-phenanthroline derivatives via three-component reaction of aromatic aldehyde, quinolin-6-amine, and n-butylvinyl ether is described using iodine as catalyst. The features of this procedure are mild reaction conditions, good to high yields, and operational simplicity.

• 出版日期2012-9
• 单位江苏师范大学