An alkyne hydrosilylation-Hiyama coupling approach to highly functionalised 1,3-dienes

作者:McAdam Catherine A*; McLaughlin Mark G; Cook Matthew J
来源:Organic Chemistry Frontiers, 2015, 2(5): 510-514.
DOI:10.1039/c5qo00002e

摘要

A high yielding and robust protocol for the stereodefined synthesis of 1,3-dienes has been established through a hydrosilylation-Hiyama coupling strategy. In all cases the products were formed as single E, E isomers and conditions are tolerant of a wide range of functional groups not compatible with other methods.

  • 出版日期2015