Acutaxylines A and B, two novel triterpenes from Dysoxylum acutangulum

作者：Ismail Intan Safinar; Nagakura Yuta; Hirasawa Yusuke; Hosoya Takahiro; Lazim Mohd Izwan Mohd; Lajis Nordin Hj; Morita Hiroshi^*

来源：Tetrahedron Letters, 2009, 50(34): 4830-4832.

DOI：10.1016/j.tetlet.2009.05.110

Two novel triterpenes, acutaxylines A (1) and B (2) consisting of a cyclopentenone side chain at C-17 and an oxepan-2-ol, were isolated from the leaves of Dysoxylum acutangulum. The relative stereochemistry of 1 and 2 was determined by NOESY correlations. Acutaxyline B showed moderate cytotoxicity against human blood premyelocytic leukemia cells.

• 出版日期2009-8-26