科研之友
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摘要
"Pedra hume cad" is the common name of five species of Myrcia genus used as traditional medicine for the treatment of diabetes mellitus. In this study, different extracts from Myrcia Myrcia sphaerocarpa, and Myrcia speciosa were investigated for the first time, to identify their phenolic compounds (being 3-O-rhamnoside derivatives of myricetin and quercetin the major ones) and in vitro inhibitory potential against alpha-glucosidase and alpha-amylase. These extracts inhibited 90-500 times more alpha-glucosidase (IC50 = 0.7 to 4.1 mu g ml(-1)) than acarbose and displayed a mild inhibition against alpha-amylase (IC50= 6.1 to 29 mu g mL(-1)). 2015 Elsevier B.V.
- 出版日期2016-1-25
