Asymmetric catalysis with chiral primary amine-based organocatalysts

作者:Xu Li Wen; Luo Jie; Lu Yixin*
来源:Chemical communications, 2009, (14): 1807-1821.
DOI:10.1039/b821070e

摘要

In the past few years, primary amine catalysts derived from natural amino acids, Cinchona alkaloids and other chiral amines have emerged as readily available, highly versatile and extremely powerful catalysts in asymmetric synthesis. They have been demonstrated to be effective catalysts in a wide range of enantioselective organic reactions. In comparison with secondary amine-mediated transformations, the use of primary amine organocatalysts has often been shown to be complementary or superior.