An efficient one-pot protocol for the conversion of benzaldehydes into tetrazole analogs

作者:Khan Khalid Mohammed*; Fatima Itrat; Saad Syed Muhammad; Taha Muhammad; Voelter Wolfgang
来源:Tetrahedron Letters, 2016, 57(5): 523-524.
DOI:10.1016/j.tetlet.2015.12.067

摘要

An efficient protocol has been developed for the one-pot synthesis of tetrazole derivatives in moderate to good yields starting from substituted benzaldehydes and proceeding via non-isolated oxime and nitrile intermediates. The structures of the desired products were confirmed by IR, and NMR spectroscopy as well as mass spectrometry. A plausible reaction mechanism is also discussed.

  • 出版日期2016-2-3