Neuro-Ophthalmic Syndromes and Processing Speed in Multiple Sclerosis

作者:Costa Silvana L*; Goncalves Oscar F; Chiaravalloti Nancy D; DeLuca John; Almeida Jorge
来源:Journal of Neuro-Ophthalmology, 2016, 36(1): 23-28.
DOI:10.1097/WNO.0000000000000272

摘要

The impact of prior neuro-ophthalmic syndromes on the performance on vision-based neuropsychological tasks in patients with multiple sclerosis (MS) is unknown. Two groups of MS participants, one with (Msos+) and the other without (Msos-), a history of neuro-ophthalmic syndromes, underwent neuropsychological assessment and were compared with healthy age- and education-matched controls (HC). Participants with Msos+ performed significantly worse on the symbol digit modalities test than the Msos- (P < 0.03) and the HC groups (P < 0.01) and coding (P < 0.01). A clinical history of neuro-ophthalmic syndromes is associated with reduced performance on visual processing speed tasks.