科研之友
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摘要
Lomerizine is a calcium channel blocker that selectively blocks L-and T-type Ca2+ channels, but it is effectively insoluble under physiological conditions. Herein we show that lomerizine can be released from a nanoparticle-based carrier by intracellular protonation in PC12 cells, suppressing Ca2+ influx in these cells in response to glutamate.
- 出版日期2012
