Determination of Serotonin on a Glassy Carbon Electrode Modified by Electropolymerization of Meso-Tetrakis(2-aminophenyl)porphyrin and Single Walled Carbon Nanotubes

作者：Kim Seul Ki; Ahmed Mohammad Shamsuddin; Jeong Haesang; You Jung Min; Jeon Seungwon^*

来源：Journal of Nanoscience and Nanotechnology, 2011, 11(3): 2407-2412.

DOI：10.1166/jnn.2011.3523

• Meso-Tetrakis(2-aminophenyl)porphyrin
• Single Walled Carbon Nanotubes
• Serotonin
• Modified Electrode
• Biosensor

A chemically modified electrode [poly(TAPP)-SWNT/GCE] was prepared by electropolymerization of meso-tetrakis(2-aminophenyl)porphyrin (TAPP)-single walled carbon nanotubes (SWNT) on the surface of a glassy carbon electrode (GCE). This modified electrode was employed as an electrochemical biosensor for the determination of serotonin concentration and exhibited a typical enhance effect on the current response of serotonin and lower oxidation overpotential. The biosensor was very effective to determined 5-HT in a mixture. The linear response was in the range 2.0 x 10(-7) to 1.0 x 10(-5) M, with a correlation coefficient of 0.999 [i(p)(mu A) = 3.406 C (mu M) + 0.132] on the anodic current, with a detection limit of 1 x 10(-9) M. Due to the relatively low currents and different potentials in the electrochemical responses to ascorbic acid and dopamine, the modified electrode is a useful and effective sensing device for the selective and sensitive serotonin determination in the presence of ascorbic acid and dopamine.

• 出版日期2011-3