Tomography of human trabecular bone with a laser-wakefield driven x-ray source

作者：Cole J M; Wood J C; Lopes N C; Poder K; Abel R L; Alatabi S; Bryant J S J; Jin A; Kneip S; Mecseki K; Parker S; Symes D R; Sandholzer M A; Mangles S P D; Najmudin Z

来源：Plasma Physics and Controlled Fusion, 2016, 58(1): 014008.

DOI：10.1088/0741-3335/58/1/014008

• laser wakefield
• betatron
• x-ray
• tomography
• bone

A laser-wakefield driven x-ray source is used for the radiography of human bone. The betatron motion of accelerated electrons generates x-rays which are hard (critical energy E-crit > 30 keV), have small source size (<3 mu m) and high average brightness. The x-rays are generated from a helium gas cell which is near-instantly replenishable, and thus the average photon flux is limited by the repetition rate of the driving laser rather than the breakdown of the x-ray source. A tomograph of a human bone sample was recorded with a resolution down to 50 mu m. The photon flux was sufficiently high that a radiograph could be taken with each laser shot, and the fact that x-ray beams were produced on 97% of shots minimised failed shots and facilitated full micro-computed tomography in a reasonable time scale of several hours, limited only by the laser repetition rate. The x-ray imaging beamline length (not including the laser) is shorter than that of a synchrotron source due to the high accelerating fields and small source size. Hence this interesting laboratory-based source may one day bridge the gap between small microfocus x-ray tubes and large synchrotron facilities.

• 出版日期2016-1