Population genetic data of Investigator HDplex markers in Han population from Southern China

作者：Liu, Qiuling; Nan, Hailun; He, Xin; Wu, Weiwei; Lu, Dejian^*

来源：International Journal of Legal Medicine, 2019, 133(1): 77-79.

DOI：10.1007/s00414-018-1796-6

• Short tandem repeat (STR)
• Allele frequency
• Chinese
• Investigator HDplex kit

Allele frequencies and forensic statistical parameters for 12 STRs contained in the Investigator HDplex Kit (D2S1360, D3S1744, D4S2366, D5S2500, SE33, D6S474, D7S1517, D8S1132, D10S2325, D12S391, D18S51, and D21S2055) were estimated from a sample of 503 unrelated individuals from the Guangdong Han population of South China. No significant departure from the Hardy-Weinberg equilibrium or genetic linkage disequilibrium was observed (after Bonferroni correction). The expected heterozygosity ranged from 0.6411 to 0.9414. The allele frequencies in Guangdong Han significantly differed from that in Shanghai Han, Korea, Northern Italian, Swedish, Dutch, Somalia, and Argentinean populations at 2 to 12 loci. The markers included in the kit have highly polymorphic information that could be used for forensic DNA analysis as potential tools for differentiating Han population from other populations in the world.

• 出版日期2019-1
• 单位中山大学; 司法部司法鉴定科学技术研究所