Attitude towards ovarian tissue and oocyte cryopreservation for non-medical reasons: a cross-sectional study

作者：Woodtli Nada; von Wolff Michael; Bitterlich Norman; Stute Petra^*

来源：Archives of Gynecology and Obstetrics, 2018, 298(1): 191-198.

DOI：10.1007/s00404-018-4778-5

• Cryopreservation
• Ovarian tissue
• Oocyte
• Hormone therapy
• Fertility

To assess the attitude towards ovarian tissue and oocyte cryopreservation for non-medical reasons.
Cross-sectional electronic survey in 248 Swiss women aged 15-35 years, nationally representative for educational level.
Most women did not worry about an age-related fertility decline. Two-thirds of women would consider using hormone therapy (HT) for menopausal symptom relief although concerns about side effects and risks were still high. Acceptance of cryopreservation of oocytes (19%) or ovarian tissue (13%) for postponing fertility or menopause was generally low, but increased (37%) if both goals could be achieved with one surgery. Cryopreservation of ovarian tissue for postponing menopause was acceptable for 22% of women. Not having a suitable partner until age 35 increased the likelihood of considering postponing fertility by cryopreservation (p < 0.001) and had a stronger impact on that decision than the factor "pursuing a career" (p < 0.001).
More education on age-related fertility decline, menopause and HT (benefit-risk ratio) is needed. Furthermore, the political and socioeconomic discussion should focus on women's needs, especially on compatibility of career and family.

• 出版日期2018-7