Adverse Cardiovascular Effects from the Use of Anabolic-Androgenic Steroids as Ergogenic Resources

作者：Pereira dos Santos Marcos Antonio; Coutinho de Oliveira Caio Victor; Silva Alexandre Sergio

来源：Substance Use & Misuse, 2014, 49(9): 1132-1137.

DOI：10.3109/10826084.2014.903751

• anabolic agents
• doping in sports
• cardiovascular iseases
• hypertension
• cardiac hypertrophy

This review evaluates the documented cardiovascular functioning among anabolic-androgenic steroid (AAS) users. AAS users manifest a reduction in HDL cholesterol, increased inflammatory markers, and oxidative stress. Strong evidence associating AAS use with blood pressure at hypertensive levels, as well as hypertrophy and cardiac dysfunction has also been reported. Both epidemiological and autopsy studies attest the relationship between AAS use and early mortality. The review's limitations are noted.

• 出版日期2014