Arterial spin-labeling MR imaging in moyamoya disease compared with clinical assessments and other MR imaging finings

作者：Noguchi Tomoyuki^*; Kawashima Masatou; Nishihara Masashi; Hirai Tetsuyoshi; Matsushima Toshio; Irie Hiroyuki

来源：European Journal of Radiology, 2013, 82(12): E840-E847.

DOI：10.1016/j.ejrad.2013.08.040

• Magnetic resonance imaging
• Arterial spin-labeling
• Perfusion
• Moyamoya disease
• Magnetic resonance angiography

Purpose: Our purpose was to identify the causal factors for the perfusion distribution obtained with ASL-MRI by comparing ASL-MRI with clinical information and other MRI findings in moyamoya disease. %26lt;br%26gt;Methods: Seventy-one patients with moyamoya disease underwent ASL-MRI and other MRI, including fluid-attenuated inversion recovery imaging (FLAIR) and three-dimensional time-of-flight magnetic resonance angiography (MRA) on 3.0-Tesla MRI system. Cerebral blood flow (CBF) values (ASL values) for the cerebral hemispheres (142 sides) were measured on CBF maps generated by ASL-MRI. Relationships between the ASL values and the following 9 factors were assessed: sex, family history, revascularization surgery, age at MR exam, age at onset, the steno-occlusive severity on MRA (MRA score), degree of basal collaterals, degree of leptomeningeal high signal intensity seen on FLAIR, and size of ischemic or hemorrhagic cerebrovascular accident lesion (CVA score). %26lt;br%26gt;Results: Patients with a family history had significantly higher ASL values than those without such a history. There were significant negative correlations between ASL values and age at MR exam, MRA score, and CVA score. %26lt;br%26gt;Conclusions: ASL-MRI may have cause-and-effect or mutual associations with family history, current patient age, size of CVA lesion, and intracranial arterial steno-occlusive severity in Moyamoya disease.

• 出版日期2013-12