A novel paradodecatungstate-B compound decorated by transition metal copper, Na2Cu5(H2O)(24)(OH)(2)[H2W12O42]center dot 10H(2)O: Synthesis, structure and antitumor activities

作者：Qu Xiaoshu^*; Yang Yanyan; Yu Xiaoyang; Lv Ze; Ji Mingshuang; Feng SuYang

来源：Inorganic Chemistry Communications, 2015, 60: 126-130.

DOI：10.1016/j.inoche.2015.08.006

• Paradodecatungstate-B compound
• Crystal structure
• Antitumor activity

A new paradodecatungstate-B compound decorated by transition metal copper, Na2Cu5(H2O)(24)(OH)(2)[H2W12O42]center dot 10H(2)O (1), has been synthesized by convenient aqueous solution method and structurally characterized by singlecrystal X-ray diffraction, IR spectrum, elemental analysis and TGA. The compound crystallizes in the triclinic P1 space group with a = 10.7140(8) angstrom, b = 12.9476(9) angstrom, c = 13.6696(10) angstrom, alpha = 73.56 degrees, beta = 75.73 degrees, gamma = 67.69 degrees, V = 1661.8(2) angstrom(3) and Z = 1. In compound 1, polyanion of [H2W12O42](10-) acts as a dodecadentate ligand that links copper and sodium cations, forming a remarkable three-dimensional framework. The experiment of antitumor activities in vitro shows that the title compound exhibits remarkable inhibitory actions on human cervical carcinoma HeLa cells, ovarian carcinoma SKOV-3 cells, hepatoma HepG2 cells and neuroblastoma SHY5Y cells.

• 出版日期2015-10
• 单位吉林化工学院