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摘要
The objective of this study was to describe unusual neurological complications secondary to haemostatic disorders in critically ill dogs The Clinical Cases for this study were identified from the population of dogs examined at the Veterinary Teaching Hospital (VTH) in a six months period Patients were Included if they fit two selection criteria presence of an haemostatic disorder documented by CBC and coagulation profile, and neurological complications secondary to the haemostatic disorder documented by means of clinical signs, necropsy and other complementary exams. Four dogs satisfied the inclusion criteria, one of these was referred for evaluation of neurological disease and the remaining cases developed neurological signs in the ICU Three of the patients evaluated showed neurological complications associated to bleeding, while the Fourth had signs secondary to arterial thrombosis Three dogs died or were euthanized due to poor prognosis, and the outcome was excellent in the surviving dog with a multifocal (spinal cold and forebrain) vascular problem secondary to DIC The post mortem-mortem examination performed in 2/3 patients confirmed the presence of haemorrhages, fibrin thrombi, and ischemia-related lesions in the CNS New or unique information provided Our observations suggest that coagulation disorders should be considered when neurological complications develop in critically ill patients In addition, there is a high variability, between detectable alterations in coagulation profiles and real haemostatic status in critically ill patients An early and complete in vitro haemostatic status evaluations, as well as treatment of the underlying disorder are essential to be able to anticipate these severe and unpredictable complications in intensive care patients
- 出版日期2010
