Acute ST-Elevation Myocardial Infarction, a Unique Complication of Recreational Nitrous Oxide Use

作者：Indraratna Praveen^*; Alexopoulos Chris; Celermajer David; Alford Kevin

来源：Heart Lung and Circulation, 2017, 26(8): E41-E43.

DOI：10.1016/j.hlc.2017.01.019

• Acute myocardial infarction
• Coronary artery disease
• Nitrous oxide
• Homocysteine

A 28-year-old male was admitted to hospital with an acute ST-elevation myocardial infarction. This was in the context of recreational abuse of nitrous oxide. The prevalence of nitrous oxide use in Australia has not been formally quantified, however it is the second most commonly used recreational drug in the United Kingdom. Nitrous oxide has previously been shown to increase serum homocysteine levels. This patient was discovered to have an elevated homocysteine level at baseline, which was further increased after nitrous oxide consumption. Homocysteine has been linked to endothelial dysfunction and coronary atherosclerosis and this case report highlights one of the dangers of recreational abuse of nitrous oxide.

• 出版日期2017-8