Analysis of the complete genome sequence of the archaeon Pyrococcus chitonophagus DSM 10152 (formerly Thermococcus chitonophagus)

作者：Papadimitriou Konstantinos; Baharidis Panagiotis K; Georgoulis Anastasios; Engel Marion; Louka Maria; Karamolegkou Georgia; Tsoka Aggeliki; Blom Jochen; Pot Bruno; Malecki Piotr; Rypniewski Wojciech; Huber Harald; Schloter Michael; Vorgias Constantinos^*

来源：Extremophiles, 2016, 20(3): 351-361.

DOI：10.1007/s00792-016-0826-x

• Genome analysis
• Pyrococcus chitonophagus
• Chitinolytic activity
• Hyperthermophilic archeon

Here we analyze the first complete genome sequence of Pyrococcus chitonophagus. The archaeon was previously suggested to belong to the Thermococcus rather than the Pyrococcus genus. Whole genome phylogeny as well as whole proteome comparisons using all available complete genomes in Thermococcales clearly showed that the species belongs to the Pyrococcus genus. P. chitonophagus was originally isolated from a hydrothermal vent site and it has been described to effectively degrade chitin debris, and therefore is considered to play a major role in the sea water ecology and metabolic activity of microbial consortia within hot sea water ecosystems. Indeed, an obvious feature of the P. chitonophagus genome is that it carries proteins showing complementary activities for chitin degradation, i.e. endo- and exo-chitinase, diacetylchitobiose deacetylase and exo-beta-d glucosaminidase activities. This finding supports the hypothesis that compared to other Thermococcales species P. chitonophagus is adapted to chitin degradation.

• 出版日期2016-5