Next-generation sequencing approaches for genetic mapping of complex diseases

作者：Casals Ferran^*; Idaghdour Youssef; Hussin Julie; Awadalla Philip

来源：Journal of Neuroimmunology, 2012, 248(1-2): 10-22.

DOI：10.1016/j.jneuroim.2011.12.017

• Next-generation sequencing
• Complex disease
• Genomics

The advent of next generation sequencing technologies has opened new possibilities in the analysis of human disease. In this review we present the main next-generation sequencing technologies, with their major contributions and possible applications to the study of the genetic etiology of complex diseases.

• 出版日期2012-7-15