按酵母基因优化的HPV6型L1蛋白在大肠杆菌中高效表达

作者：李平川张晓光周玲曾毅

来源：病毒学报, 2004, (03): 266-269.

• 人乳头瘤病毒6型
• L1蛋白
• Pichiapastoris
• 大肠杆菌
• 基因优化
• 表达 human papillomavirus type 6
• L1 protein
• Pichia pastoris
• Escherichia coli
• gene optimization
• expression

Human papillomavirus 6(HPV6) causes a common sexually transmitted disease,the genital warts.L1-capsid protein is a highly promising preventive vaccine that has entered phase Ⅱ clinical trial.But the existing methodologies for producing L1-capsid protein in insect cells is expensive for use in develo...

• 出版日期2004
• 单位中国疾病预防控制中心病毒病预防控制所